What is the difference between Kratom and Pseudoindoxyl?

Kratom and mitragynine pseudoindoxyl are related but distinct substances:

Origin and Composition

Kratom: A natural plant product derived from the leaves of Mitragyna speciosa, containing multiple alkaloids, with mitragynine being the primary active ingredient.
Mitragynine Pseudoindoxyl: Not naturally present in kratom leaves but formed through oxidative metabolism of mitragynine or rearrangement of 7-hydroxymitragynine (7-OH).

Potency and Effects

Kratom: Contains various alkaloids with moderate potency, users have reported mood elevation and energy-boosting effects.
Mitragynine Pseudoindoxyl: Significantly more potent than kratom's primary alkaloids with users reporting similar but enhanced effects.

Availability and Research Status

Kratom: Widely available as a natural product in various forms (leaves, extracts).
Mitragynine Pseudoindoxyl: Not naturally abundant, but can be synthesized in labs. It's currently a subject of ongoing research for potential therapeutic applications.

In summary, while kratom is a complex natural product with multiple alkaloids, mitragynine pseudoindoxyl is a specific, potent compound derived from kratom's alkaloids.

Mar 26th 2025